François Inizan . Myriam Hanna . Maxim Stolyarchuk . Isaure Chauvot de Beauchêne . Luba Tchertanov

Cet article est également un hommage à François Inizan, brillant étudiant trop tôt disparu. Receptor tyrosine kinases (RTKs) are key regulators of normal cellular processes and have a critical role in the development and progression of many diseases. We communicate the first structural model of the full-length RTK KIT cytoplasmic domain, a crucial target for cancer therapy.

Nature Scientific Reports 10(5401) 2020. DOI: 10.1038/s41598-020-62460-7